Article
[Genetic polymorphism of beta-adrenergic receptors and mortality in ischemic heart disease].
Therapie - 1 Jan 2000
Jaillon Patrice, Simon Tabassome
Abstract excerpt
The genetic polymorphism of beta-2 adrenergic receptors (B2AR) could play a major role in the prognostic of patients with a coronary heart disease. Two recent epidemiological studies could support this hypothesis. In 597 patients treated by a beta-blocker and followed for 3 years after a myocardial infarction or an acute coronary syndrome, the death rate was 5.4 times higher in homozygous Arg 16 and Gln 27 B2AR...
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