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Myxovirus-1 and protein kinase haplotypes and fibrosis in chronic hepatitis C virus

24 May 2007

Abstract excerpt

UNLABELLED: Candidate genes, including myxovirus resistance-1 (Mx1), protein kinase (PKR), transforming growth factor-beta1 (TGF-beta), interleukin-10 (IL-10), and interferon-gamma (IFN-gamma), were evaluated for associations with liver fibrosis in 374 treatment-naive patients with genotype-1 chronic HCV infection [194 Caucasian Americans (CAs) and 180 African Americans (AAs)], using a genetic haplotype approach....

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PMID: 17526009
DOI: 10.1002/hep.21636

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