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Article

Increased Smad1 expression and transcriptional activity enhances trans-differentiation of hepatic stellate cells.

Journal of cellular physiology - 1 Sept 2007

Shen Hong, Fan Jianghong, Burczynski Frank, Minuk Gerald Y, Cattini Peter, Gong Yuewen

Abstract excerpt

Smad1 is a receptor-activated intracellular signaling protein, which mediates signal transduction of bone morphogenetic proteins. Current study investigated the expression and transcriptional activity of Smad1 during hepatic stellate cell (HSC) activation. Rat HSCs were isolated from rats at 1, 2...

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Identifiers

PMID: 17525996
DOI: 10.1002/jcp.21074

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17525996-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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