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Article

The forkhead transcription factor FoxO1 regulates proliferation and transdifferentiation of hepatic stellate cells.

Gastroenterology - 1 Apr 2007

Adachi Masayuki, Osawa Yosuke, Uchinami Hiroshi, Kitamura Tadahiro, Accili Domenico, Brenner David A

Abstract excerpt

BACKGROUND & AIMS: The Forkhead box gene, group O (FoxO) family of Forkhead transcription factors is phopsphorylated and inactivated by the phosphatidylinositol 3-kinase (PI3K)/AKT pathway and regulates a variety of cellular functions. Hepatic stellate cells (HSCs) play a crucial role in liver fi...

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Identifiers

PMID: 17408630
DOI: 10.1053/j.gastro.2007.01.033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17408630-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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