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Article

Guinea pig-adapted foot-and-mouth disease virus with altered receptor recognition can productively infect a natural host.

Journal of virology - 1 Aug 2007

Núñez José I, Molina Nicolas, Baranowski Eric, Domingo Esteban, Clark Stuart, Burman Alison, Berryman Stephen, Jackson Terry, Sobrino Francisco

Abstract excerpt

We report that adaptation to infect the guinea pig did not modify the capacity of foot-and-mouth disease virus (FMDV) to kill suckling mice and to cause an acute and transmissible disease in the pig, an important natural host for this pathogen. Adaptive amino acid replacements (I(248)-->T in 2C,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17522230
DOI: 10.1128/JVI.00340-07
PMCID: PMC1951369

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17522230-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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