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Article

Pretreatment sequence diversity differences in the full-length hepatitis C virus open reading frame correlate with early response to therapy.

Journal of virology - 1 Aug 2007

Donlin Maureen J, Cannon Nathan A, Yao Ermei, Li Jia, Wahed Abdus, Taylor Milton W, Belle Steven H, Di Bisceglie Adrian M, Aurora Rajeev, Tavis John E

Abstract excerpt

Pegylated alpha interferon and ribavirin therapy for hepatitis C virus (HCV) genotype 1 infection fails for half of Caucasian American patients (CA) and more often for African Americans (AA). The reasons for these low response rates are unknown. HCV is highly genetically variable, but it is unknown how this variability affects response to therapy. To assess effects of viral diversity on response to therapy, the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17522222
DOI: 10.1128/JVI.00487-07
PMCID: PMC1951276

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Pretreatment sequence diversity differences in the full-length hepatitis C virus open reading frame correlate with early response to therapy.PMID 17522222Read ↗

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