Article
Peginterferon pharmacokinetics in African American and Caucasian American patients with hepatitis C virus genotype 1 infection.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 May 2008
Howell Charles D, Dowling Thomas C, Paul Marika, Wahed Abdus S, Terrault Norah A, Taylor Milton, Jeffers Lennox, Hoofnagle Jay H
Abstract excerpt
BACKGROUND & AIMS: The relationship between serum peginterferon pharmacokinetics and pharmacodynamics and the early virologic response (EVR) to peginterferon and ribavirin therapy was assessed in patients with chronic hepatitis C virus (HCV) genotype 1 infection. METHODS: A total of 333 patients (160 African Americans [AA] and 173 Caucasian Americans [CA]) who received peginterferon alpha-2a (180 microg/wk)...
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