Article
Complexity and diversity of hepatitis C virus RNA in african americans and whites: analysis of the envelope-coding domain.
The Journal of infectious diseases - 1 Aug 2004
Keenan Erica D, Rouster Susan D, Shire Norah J, Horn Paul S, Sherman Kenneth E
Abstract excerpt
African Americans infected with hepatitis C virus (HCV) are less responsive than whites to interferon-based therapy. HCV quasi species have been implicated. Quasi-species complexity and diversity were evaluated in matched African American and white individuals. Complexity and diversity in the first hypervariable region were similar in the 2 groups. Both the frequency of nonsynonymous amino acid substitutions and...
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