Article
SM22alpha: the novel phenotype marker of injured glomerular epithelial cells in anti-glomerular basement membrane nephritis.
Nephron. Experimental nephrology - 1 Jan 2007
Ogawa Asa, Sakatsume Minoru, Wang Xingzhi, Sakamaki Yunichi, Tsubata Yutaka, Alchi Bassam, Kuroda Takeshi, Kawachi Hiroshi, Narita Ichiei, Shimizu Fujio, Gejyo Fumitake
Abstract excerpt
BACKGROUND/AIMS: Our previous comprehensive analysis of the genes expressed in kidneys with anti-glomerular basement membrane (GBM) nephritis using DNA microarrays showed that SM22alpha was one of the highly expressed genes. SM22alpha is a 22-kDa cytoskeletal protein that is exclusively expressed in smooth muscle cells. We investigated the localization of SM22alpha at mRNA and protein levels, and its pathological...
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