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Article

Increased Ca2+ storage capacity of the skeletal muscle sarcoplasmic reticulum of transgenic mice over-expressing membrane bound calcium binding protein junctate.

Journal of cellular physiology - 1 Nov 2007

Divet Alexandra, Paesante Silvia, Grasso Cristiano, Cavagna Dario, Tiveron Cecilia, Paolini Cecilia, Protasi Feliciano, Huchet-Cadiou Corinne, Treves Susan, Zorzato Francesco

Abstract excerpt

Junctate is an integral sarco(endo)plasmic reticulum protein expressed in many tissues including heart and skeletal muscle. Because of its localization and biochemical characteristics, junctate is deemed to participate in the regulation of the intracellular Ca2+ concentration. However, its physiological function in muscle cells has not been investigated yet. In this study we examined the effects of junctate...

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PMID: 17516551
DOI: 10.1002/jcp.21121

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