Article
Parent-of-origin dependent gene-specific knock down in mouse embryos.
Biochemical and biophysical research communications - 6 Jul 2007
Iqbal Khursheed, Kues Wilfried A, Niemann Heiner
Abstract excerpt
In mice hemizygous for the Oct4-GFP transgene, the F1 embryos show parent-of-origin dependent expression of the marker gene. F1 embryos with a maternally derived OG2 allele (OG2(mat)/-) express GFP in the oocyte and during preimplantation development until the blastocyst stage indicating a matern...
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