Article
[Susceptibility markers in Tunisian first-degree relatives of patients with type 1 diabetes].
Annales d'endocrinologie - 1 Jun 2007
Laadhar L, Gassara A, Mahfoudh N, Ben Hadj hmida Y, Kamoun T, Ben Ayed M, Rekik N, Mahfoudh A, Rebai A, Makni H, Abid M, Hachicha M, Masmoudi H
Abstract excerpt
To identify the profile of anti-pancreas autoantibodies and elucidate the HLA DRB1, DQB1 polymorphism in Tunisian first-degree relatives of patients with type 1 diabetes, we recruited 96 relatives from 21 families with at least one diabetic child. Islet cell antibodies (ICA) were detected by immunofluorescence on monkey pancreas; glutamate decarboxylase (GADA), IA2 (IA2-A) and insulin (IAA) antibodies were...
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