Article
Using molecular dynamics to map interaction networks in an aminoacyl-tRNA synthetase.
Proteins - 15 Aug 2007
Budiman Michael E, Knaggs Michael H, Fetrow Jacquelyn S, Alexander Rebecca W
Abstract excerpt
Long-range functional communication is a hallmark of many enzymes that display allostery, or action-at-a-distance. Many aminoacyl-tRNA synthetases can be considered allosteric, in that their trinucleotide anticodons bind the enzyme at a site removed from their catalytic domains. Such is the case...
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