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Article

Association between DNA repair gene polymorphisms and p53 alterations in Japanese patients with muscle-invasive bladder cancer.

Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2006

Sakano Shigeru, Matsumoto Hiroaki, Yamamoto Yoshiaki, Kawai Yoshihisa, Eguchi Satoshi, Ohmi Chietaka, Matsuyama Hideyasu, Naito Katsusuke

Abstract excerpt

OBJECTIVE: DNA repair enzymes play a vital role in protecting the genome from carcinogens, several of which can cause mutations in the TP53 gene in bladder cancer. Some single nucleotide polymorphisms (SNPs) in DNA repair genes reportedly modulate the repair capacity. This study aimed to clarify the effect of these functional SNPs on the alteration of p53 in muscle-invasive bladder cancer. METHODS: We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to X-ray Repair Cross Complementing Protein 1

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Source

Identifiers

PMID: 17374967
DOI: 10.1159/000099124

Genes

XPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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