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Article

XPC epigenetic silence coupled with p53 alteration has a significant impact on bladder cancer outcome.

The Journal of urology - 1 Jul 2010

Yang Jin, Xu Zhigang, Li Jie, Zhang Rong, Zhang Guizheng, Ji Huixiang, Song Bo, Chen Zhiwen

Abstract excerpt

PURPOSE: Varied XPC genetics are related to bladder cancer susceptibility. We determined whether decreased XPC expression influences bladder cancer malignancy and clinical outcome. MATERIALS AND METHODS: Changes in XPC and p53 expression were detected by immunochemistry in 108 bladder cancers, including 29 papillary neoplasms of low malignant potential, and 48 low and 31 high grade lesions, of which 47 were stage...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20488473
DOI: 10.1016/j.juro.2010.03.044

Genes

XPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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