Article
Polymorphisms of interferon-gamma, interleukin-10, and interleukin-12 genes in myasthenia gravis.
Human immunology - 1 Jun 2007
Yilmaz Vuslat, Tütüncü Yildiz, Bariş Hasbal N, Parman Yesim, Serdaroglu Piraye, Deymeer Feza, Saruhan-Direskeneli Güher
Abstract excerpt
To assess the involvement of polymorphisms in genetic susceptibility to myasthenia gravis (MG), this study analyzed four polymorphisms of interferon (IFN)-gamma, interleukin (IL)-10, and IL-12 genes in 115 patients and 204 healthy controls (HC). IFNG +874T carriers were less frequent in MG, in patients with anti-acetylcholine receptor (AChR) (63%) and anti-titin (56.2%) antibodies compared with HC (p = 0.01 for...
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