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Article

An enhanced risk of basal cell carcinoma is associated with particular polymorphisms in the VDR and MTHFR genes.

Experimental dermatology - 1 Oct 2011

Lesiak Aleksandra, Norval Mary, Wodz-Naskiewicz Karolina, Pawliczak Rafal, Rogowski-Tylman Michal, Sysa-Jedrzejowska Anna, Sobjanek Michal, Wlodarkiewicz Adam, Narbutt Joanna

Abstract excerpt

BACKGROUND: Vitamin D and folate are influenced by ultraviolet radiation (UVR), and both are implicated in skin carcinogenesis. Polymorphisms in the genes involved in the metabolism of these two compounds may alter the risk of basal cell carcinoma (BCC). OBJECTIVE: To assess the frequency of four polymorphisms in the gene encoding the vitamin D receptor (VDR) (FokI, BsmI, TaqI and ApaI) and two in the gene...

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Source

Identifiers

PMID: 21732987
DOI: 10.1111/j.1600-0625.2011.01328.x

Genes

MTHFR
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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