Article
Chromosome 3 status in uveal melanoma: a comparison of fluorescence in situ hybridization and single-nucleotide polymorphism array.
Investigative ophthalmology & visual science - 5 Jun 2012
Singh Arun D, Aronow Mary E, Sun Yang, Bebek Gurkan, Saunthararajah Yogen, Schoenfield Lynn R, Biscotti Charles V, Tubbs Raymond R, Triozzi Pierre L, Eng Charis
Abstract excerpt
PURPOSE: To compare fluorescence in situ hybridization (FISH) using a centromeric probe for chromosome 3 (CEP3) and 3p26 locus-specific probe with single-nucleotide polymorphism array (SNP-A) analysis in the detection of high-risk uveal melanoma. METHODS: Fifty cases of uveal melanoma (28 males, 22 females) treated by enucleation between 2004 and 2010 were analyzed. Fresh tissue was used for FISH and SNP-A...
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