Article
Hepatitis B virus genotype E surface antigen detection with different immunoassays and diagnostic impact of mutations in the preS/S gene.
Medical microbiology and immunology - 1 Dec 2007
Olinger Christophe M, Weber Bernard, Otegbayo Jesse A, Ammerlaan Wim, van der Taelem-Brulé Natascha, Muller Claude P
Abstract excerpt
The major neutralizing epitope, the "a" determinant of the hepatitis B virus (HBV) genotype E surface antigen (HBsAg) is most divergent from that of genotype A, which is used for preparing monoclonal antibodies used in commercially available HBV reagents. To evaluate the performance of the latest generation of HBsAg detection assays with respect to genotype E HBsAg. Three commercial assays were evaluated using...
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