Article
Diagnostic impact of the genetic variability of the hepatitis B virus surface antigen gene.
Journal of medical virology - 1 Jan 2006
Weber Bernard
Abstract excerpt
The genetic variability of hepatitis B virus (HBV) represents a challenge for the sensitivity of immunologic and molecular based assays. Genotyping studies show that the genetic diversity of HBV is very high even in industrialized countries. The analytical sensitivity of HBsAg and anti-HBs assays may be dependent on HBV genotype or subtype and could possibly lead to false negative results in samples with...
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