Article
Association of GST genetic polymorphisms with the susceptibility to hepatocellular carcinoma (HCC) in Chinese population evaluated by an updated systematic meta-analysis.
PloS one - 1 Jan 2013
Liu Kui, Zhang Lu, Lin Xialu, Chen Liangliang, Shi Hongbo, Magaye Ruth, Zou Baobo, Zhao Jinshun
Abstract excerpt
BACKGROUND: Due to the possible involvement of Glutathione S-transferase Mu-1 (GSTM1) and Glutathione S-transferase theta-1 (GSTT1) in the detoxification of environmental carcinogens, environmental toxins, and oxidative stress products, genetic polymorphisms of these two genes may play important roles in the susceptibility of human being to hepatocellular carcinoma. However, the existing research results are not...
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