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Article

Genome wide comparison of Ethiopian Leishmania donovani strains reveals differences potentially related to parasite survival.

PLoS genetics - 1 Jan 2018

Zackay Arie, Cotton James A, Sanders Mandy, Hailu Asrat, Nasereddin Abedelmajeed, Warburg Alon, Jaffe Charles L

Abstract excerpt

Leishmania donovani is the main cause of visceral leishmaniasis (VL) in East Africa. Differences between northern Ethiopia/Sudan (NE) and southern Ethiopia (SE) in ecology, vectors, and patient sensitivity to drug treatment have been described, however the relationship between differences in parasite genotype between these two foci and phenotype is unknown. Whole genomic sequencing (WGS) was carried out for 41 L....

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Identifiers

PMID: 29315303
DOI: 10.1371/journal.pgen.1007133
PMCID: PMC5777657

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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