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Article

Regulation of Cited2 expression provides a functional link between translational and transcriptional responses during hypoxia.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Jun 2007

van den Beucken Twan, Magagnin Michael G, Savelkouls Kim, Lambin Philippe, Koritzinsky Marianne, Wouters Bradly G

Abstract excerpt

BACKGROUND AND PURPOSE: Protein synthesis rates are greatly reduced under hypoxic conditions as a consequence of an overall inhibition of mRNA translation. Certain specific mRNA species have the ability to escape this general translational repression. At the cellular level this results in differential protein expression during hypoxic conditions. The objective of this study was to characterize the translational...

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Identifiers

PMID: 17499866
DOI: 10.1016/j.radonc.2007.04.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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