Article
Translational control of Nrf2 within the open reading frame.
Biochemical and biophysical research communications - 19 Jul 2013
Perez-Leal Oscar, Barrero Carlos A, Merali Salim
Abstract excerpt
Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) is a transcription factor that is essential for the regulation of an effective antioxidant and detoxifying response. The regulation of its activity can occur at transcription, translation and post-translational levels. Evidence suggests that under environmental stress conditions, new synthesis of Nrf2 is required - a process that is regulated by translational...
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