Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide detection of recurring sites of uniparental disomy in follicular and transformed follicular lymphoma.

Leukemia - 1 Jul 2007

Fitzgibbon J, Iqbal S, Davies A, O'shea D, Carlotti E, Chaplin T, Matthews J, Raghavan M, Norton A, Lister T A, Young B D

Abstract excerpt

Single-nucleotide polymorphism (SNP) array analysis was performed using the 10K GeneChip array on a series of 26 paired follicular lymphoma (FL) and transformed-FL (t-FL) biopsies and the lymphoma cell lines SCI-1, DoHH2 and RL2261. Regions of acquired homozygosity were detected in 43/52 (83%) primary specimens with a mean of 1.7 and 3.0 aberrations in the FL and t-FL, respectively. A notable feature was the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line, Transformed
Share to Chromosomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Human

Share to Homozygote

Share to Lymphoma, Follicular

Share to Oligonucleotide Array Sequence Analysis

Share to Recombination, Genetic

Share to Uniparental Disomy

Source

Identifiers

PMID: 17495976
DOI: 10.1038/sj.leu.2404696

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide detection of recurring sites of uniparental disomy in follicular and transformed follicular lymphoma.PMID 17495976Read ↗

Regions of acquired uniparental disomy at diagnosis of follicular lymphoma are associated with both overall survival and risk of transformation.Semantic proximity Read ↗

High resolution analysis of follicular lymphoma genomes reveals somatic recurrent sites of copy-neutral loss of heterozygosity and copy number alterations that target single genes.Semantic proximity Read ↗

Genome-wide copy-number analyses reveal genomic abnormalities involved in transformation of follicular lymphoma.Semantic proximity Read ↗

Comprehensive analysis of copy number and allele status identifies multiple chromosome defects underlying follicular lymphoma pathogenesis.Semantic proximity Read ↗

SNP analysis of minimally evolved t(14;18)(q32;q21)-positive follicular lymphomas reveals a common copy-neutral loss of heterozygosity pattern.Semantic proximity Read ↗

Pathogenesis and consequences of uniparental disomy in cancer.Semantic proximity Read ↗

Genome-wide profiling of follicular lymphoma by array comparative genomic hybridization reveals prognostically significant DNA copy number imbalancesSemantic proximity Read ↗

Pan-Cancer Analysis of CDK12 Loss-of-Function Alterations and Their Association with the Focal Tandem-Duplicator PhenotypeSemantic proximity Read ↗

Genome-Wide Profiling of Acquired Uniparental Disomy Reveals Prognostic Factors in Head and Neck Squamous Cell Carcinoma.Semantic proximity Read ↗

Inherited genetic variation and overall survival following follicular lymphoma.Semantic proximity Read ↗

Analysis of secondary chromosomal alterations in 165 cases of follicular lymphoma with t(14;18)Semantic proximity Read ↗

Whole-chromosome arm acquired uniparental disomy in cancer development is a consequence of isochromosome formation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.