Article
SNP analysis of minimally evolved t(14;18)(q32;q21)-positive follicular lymphomas reveals a common copy-neutral loss of heterozygosity pattern.
Cytogenetic and genome research - 1 Jan 2012
Cheung K J, Rogic S, Ben-Neriah S, Boyle M, Connors J M, Gascoyne R D, Horsman D E
Abstract excerpt
Follicular lymphoma (FL) cases with a t(14;18)(q32;q21) and minimal or no additional karyotypic alterations, such as copy number gains and losses and/or chromosomal rearrangements, may exhibit pathologic features and a clinical behavior similar to those with more complex karyotypes. This study sought to investigate whether the copy-neutral loss of heterozygosity (cnLOH) profiles of these minimally evolved...
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