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Article

A method for in vitro assembly of hepatitis C virus core protein and for screening of inhibitors.

Analytical biochemistry - 1 Jul 2007

Fromentin Rémi, Majeau Nathalie, Laliberté Gagné Marie-Eve, Boivin Annie, Duvignaud Jean-Baptiste, Leclerc Denis

Abstract excerpt

The assembly of hepatitis C virus (HCV) is not well understood. We investigated HCV nucleocapsid assembly in vitro and the role of electrostatic/hydrophobic interactions in this process. We developed a simple and rapid in vitro assay in which the progress of assembly is monitored by measuring an increase in turbidity, thereby allowing the kinetics of assembly to be determined. Assembly is performed using a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17493576
DOI: 10.1016/j.ab.2007.03.033
PMCID: PMC2023875

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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