From Structure to Function: New Insights into Hepatitis C Virus RNA Replication

Abstract excerpt

With an estimated number of about 180 million affected people worldwide and a limited therapy option, infection with the hepatitis C virus (HCV)2 is an important medical problem. Initial limitations in propagating HCV in cell culture have been overcome step-by-step in the past few years and culminated in the recent development of a system allowing efficient propagation of infectious HCV in tissue culture....

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