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Article

Correlation between EGFR gene mutation pattern and Akt phosphorylation in pulmonary adenocarcinomas.

Pathology international - 1 May 2007

Ikeda Satoshi, Takabe Kazuhiko, Inagaki Masaharu, Funakoshi Naoya, Suzuki Keiko, Shibata Toshikatsu

Abstract excerpt

The detection of gene mutation of epithelial growth factor receptor (EGFR) is important to predict the therapeutic effect of gefitinib. Recently, it was reported that examination of the activation of the downstream protein of EGFR is useful in the same way as the EGFR mutation. Therefore the purpose of the present paper was to determine whether activation of Akt and Erk, which are downstream proteins, and the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17493174
DOI: 10.1111/j.1440-1827.2007.02093.x

Genes

EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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