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Article

Activation status of receptor tyrosine kinase downstream pathways in primary lung adenocarcinoma with reference of KRAS and EGFR mutations.

Lung cancer (Amsterdam, Netherlands) - 1 Oct 2010

Hiramatsu Miyako, Ninomiya Hironori, Inamura Kentaro, Nomura Kimie, Takeuchi Kengo, Satoh Yukitoshi, Okumura Sakae, Nakagawa Ken, Yamori Takao, Matsuura Masaaki, Morikawa Toshiaki, Ishikawa Yuichi

Abstract excerpt

The activation status of signal transduction pathways involving receptor tyrosine kinases and its association with EGFR or KRAS mutations have been widely studied using cancer cell lines, although it is still uncertain in primary tumors. To study the activation status of main components of growth...

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Identifiers

PMID: 20117855
DOI: 10.1016/j.lungcan.2010.01.001

Genes

EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20117855-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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