Article
Identification of four new HLA-Cw alleles in the Sudanese population.
Tissue antigens - 1 Mar 2007
Elamin N E, Elbashir M I, Elkhidir I M, Elghazali G, Blasczyk R, Horn P A
Abstract excerpt
The major histocompatibility complex (MHC) is the most polymorphic region of the human genome. Human leukocyte antigen-C (HLA-C) genes are located in the class I region of MHC. Most polymorphisms of HLA class I antigens are present in exons 2 and 3, which encode the alpha1 and alpha2 domains of the HLA-A heavy chain, involved in both peptide binding and HLA-restricted recognition by the T-cell receptor. Four new...
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