Article
[Single nucleotide polymorphisms in 22 HLA-Cw alleles in Chinese Han population].
Yi chuan = Hereditas - 1 May 2010
Zeng Jian-Qiang, Xu Yun-Ping, Wang Da-Ming, Gao Su-Qing, Zou Hong-Yan, Deng Zhi-Hui
Abstract excerpt
To analyze the molecular genetic polymorphism of full-length HLA-Cw gene, a total of 28 samples with known genotypes from Chinese Han population were amplified by long-range PCR using high-fidelity Pfu polymerase. A fragment 4.5 kb in length of HLA-Cw gene was subjected to cloning and haplotype sequencing. The single nucleotide polymorphisms (SNPs) in all segments of the whole region of HLA-Cw gene were analyzed....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
