Article
Single step PCR for detection of allelic variation of MDR1 gene (P-glycoprotein) among three ethnic groups in Malaysia.
Journal of clinical pharmacy and therapeutics - 1 Jun 2007
Teh L K, Lee W L, Amir J, Salleh M Z, Ismail R
Abstract excerpt
BACKGROUND: P-glycoprotein (PgP) is the most extensively studied ATP-binding cassette (ABC) coded by MDR1 gene. To date, 29 single nucleotide polymorphisms (SNPs) have been identified; but only SNP C3435T has been correlated with intestinal PgP expression levels and shown to influence the absorpt...
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