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Article

Differential and combined effects of cardiotrophin-1 and TGF-beta1 on cardiac myofibroblast proliferation and contraction.

American journal of physiology. Heart and circulatory physiology - 1 Aug 2007

Drobic Vanja, Cunnington Ryan H, Bedosky Kristen M, Raizman Joshua E, Elimban Vinit V, Rattan Sunil G, Dixon Ian M C

Abstract excerpt

Myofibroblasts respond to an array of signals from mitogens and cytokines during the course of wound healing following a myocardial infarction (MI), and these signals may coordinate ventricular myofibroblast proliferation. Furthermore, myofibroblasts are contractile and contribute to wound contraction by imparting mechanical tension on surrounding extracellular matrix. Although TGF-beta(1), CT-1, and PDGF-BB...

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Identifiers

PMID: 17483238
DOI: 10.1152/ajpheart.00935.2006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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