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Article

The assembly of functional preinitiation complexes and transcription of 5S RNA-encoding genes containing point mutations.

Gene - 15 Nov 1991

Shastry B S, Greenstein D

Abstract excerpt

The transcription of several Syrian hamster 5S RNA-encoding genes (5S genes) containing single and multiple point mutations in and around the intragenic control region has been analyzed in a HeLa cell-free system. Although most genes with point mutations displayed normal levels of transcription, several exhibited a three- to fivefold reduction in transcription. These mutations interfere with the interaction...

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Identifiers

PMID: 1748297
DOI: 10.1016/0378-1119(91)90327-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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