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Article

Comparative mutational analysis of cis-acting RNA signals for translational frameshifting in HIV-1 and HTLV-2.

Nucleic acids research - 1 Mar 2001

Kim Y G, Maas S, Rich A

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) and human T cell leukemia virus type II (HTLV-2) use a similar mechanism for -1 translational frameshifting to overcome the termination codon in viral RNA at the end of the gag gene. Previous studies have identified two important RNA signals for frameshifting, the slippery sequence and a downstream stem-loop structure. However, there have been somewhat conflicting...

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Identifiers

PMID: 11222762
DOI: 10.1093/nar/29.5.1125
PMCID: PMC29715

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