Article
The effects of disrupting 5S RNA helical structures on the binding of Xenopus transcription factor IIIA.
Nucleic acids research - 11 Sept 1990
You Q M, Romaniuk P J
Abstract excerpt
Block mutations were constructed in helical stems II, III, IV and V of Xenopus laevis oocyte 5S RNA. The affinities of these mutants for binding to transcription factor IIIA (TFIIIA) were determined using a nitrocellulose filter binding assay. Mutations in stems III and IV had little or no effect...
Topics
- Animals
- Base Sequence
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- RNA, Ribosomal
- RNA, Ribosomal, 5S
- Transcription Factor TFIIIA
- Transcription Factors
- Xenopus laevis