Modulation of HeLa cell growth by transfected 7SL RNA and Alu gene sequences.

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Article

Modulation of HeLa cell growth by transfected 7SL RNA and Alu gene sequences.

The Journal of biological chemistry - 15 Feb 1991

Sakamoto K, Fordis C M, Corsico C D, Howard T H, Howard B H

Abstract excerpt

Alu and 7SL RNA gene sequences were tested for the potential to regulate mammalian cell growth by introducing these sequences into HeLa cells in a coupled DEAE-dextran transfection/affinity cell sorting system. Both Alu and 7SL RNA genes mediated inhibition of [3H]thymidine and [35S]methionine in...

Topics

Base Sequence
Electrophoresis, Polyacrylamide Gel
HeLa Cells
Humans
Methionine
Molecular Sequence Data
Mutation
Plasmids
RNA
RNA Polymerase III
RNA, Ribosomal
Repetitive Sequences, Nucleic Acid
Thymidine
Transcription, Genetic
Transfection

Source

Open in PubMed

Identifiers

PMID: 1704372

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1704372-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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