Article
Modulation of HeLa cell growth by transfected 7SL RNA and Alu gene sequences.
The Journal of biological chemistry - 15 Feb 1991
Sakamoto K, Fordis C M, Corsico C D, Howard T H, Howard B H
Abstract excerpt
Alu and 7SL RNA gene sequences were tested for the potential to regulate mammalian cell growth by introducing these sequences into HeLa cells in a coupled DEAE-dextran transfection/affinity cell sorting system. Both Alu and 7SL RNA genes mediated inhibition of [3H]thymidine and [35S]methionine incorporation in recipient cells. In addition, short term growth curves were performed on calcium phosphate/DNA...
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