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Article

Analysis of internal motions of interleukin-13 variant associated with severe bronchial asthma using (15)N NMR relaxation measurements.

Biochemical and biophysical research communications - 22 Jun 2007

Yoshida Yuichiro, Ohkuri Takatoshi, Takeda Chika, Kuroki Ryota, Izuhara Kenji, Imoto Taiji, Ueda Tadashi

Abstract excerpt

The single nucleotide polymorphism interleukin-13 (IL-13) R110Q is associated with severe bronchial asthma because its lower affinity leads to the augmentation of local IL-13 concentration, resulting in an increase in the signal transduction via IL-13R. Since the mutation site does not directly b...

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Identifiers

PMID: 17482144
DOI: 10.1016/j.bbrc.2007.04.128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17482144-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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