Article
A 1H-NMR study of the solution conformation of Icaria chemotactic peptide and its [Lys7] analog: effects on the physiological activity of a substitution of proline to lysine at position 7.
Biochemical and biophysical research communications - 30 Apr 1990
Shimada I, Kato K, Saito K, Kitada C, Fujino M, Nakajima T, Arata Y
Abstract excerpt
Solution conformations of Icaria chemotactic peptide isolated from the Ropalidian wasp venom and its [Lys7] analog have been analyzed by the use of two-dimensional proton nuclear resonance spectroscopy. It has been shown that Icaria chemotactic peptide takes alpha helical conformation in the C-terminal 8-13 segment with the N-terminal 1-7 segment disordered. By contrast, the [Lys7] analog takes alpha helical...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.