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Article

Fusogenic vesicular stomatitis virus for the treatment of head and neck squamous carcinomas.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery - 1 May 2007

Shin Edward J, Chang Jaime I, Choi Bryan, Wanna Georges, Ebert Oliver, Genden Eric M, Woo Savio L C

Abstract excerpt

OBJECTIVES: This study investigates the efficacy of recombinant fusogenic VSV [rVSV-NDV/F(L289A) or rVSV-F] in the treatment of head and neck squamous cell carcinoma (HNSCC). STUDY DESIGN AND SETTING: The in vitro replication and cytotoxicity of rVSV-F were studied in two human SCC cell lines, in one murine SCC cell line, and in human keratinocytes. The effects on tumor size and animal survival were investigated...

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Identifiers

PMID: 17478221
DOI: 10.1016/j.otohns.2006.11.046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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