Alkaline Phosphatase Activity of Serum Affects Osteogenic Differentiation Cultures

doi:10.1021/acsomega.1c07225

Article

Alkaline Phosphatase Activity of Serum Affects Osteogenic Differentiation Cultures

4 Apr 2022

Abstract excerpt

Fetal bovine serum (FBS) is a widely used supplement in cell culture medium, despite its known variability in composition, which greatly affects cellular function and consequently the outcome of studies. In bone tissue engineering, the deposited mineralized matrix is one of the main outcome parameters, but using different brands of FBS can result in large variations. Alkaline phosphatase (ALP) is present in FBS....

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