Article
Optimal two-stage strategy for detecting interacting genes in complex diseases.
BMC genetics - 15 Jun 2006
Ionita Iuliana, Man Michael
Abstract excerpt
BACKGROUND: The mapping of complex diseases is one of the most important problems in human genetics today. The rapid development of technology for genetic research has led to the discovery of millions of polymorphisms across the human genome, making it possible to conduct genome-wide association studies with hundreds of thousands of markers. Given the large number of markers to be tested in such studies, a...
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