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Article

Matrix metalloproteinase polymorphisms are associated with bladder cancer invasiveness.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 May 2007

Kader A Karim, Liu Jun, Shao Lina, Dinney Colin P, Lin Jie, Wang Yunfei, Gu Jian, Grossman H Barton, Wu Xifeng

Abstract excerpt

PURPOSE: Matrix metalloproteinases (MMP) promote tumor invasion and alter microenvironment. MMP levels are elevated in bladder cancer patients correlating with more advanced stage. We tested whether polymorphisms in MMP genes modify the risk of bladder cancer invasiveness and whether smoke exposure modifies this risk. EXPERIMENTAL DESIGN: Using a case-only study, we examined the association of 11...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17473191
DOI: 10.1158/1078-0432.CCR-06-1187

Genes

MMP12
MMP9
MMP1
MMP2
MMP3
MMP8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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