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Article

MMP7 and MMP8 genetic polymorphisms in bladder cancer patients

1 Jan 2013

Abstract excerpt

INTRODUCTION: Breakdown of the extracellular matrix by matrix metalloproteinases (MMPs), as we know, is one of mechanisms involved and required in tumor invasion. MMP7 is a negative prognostic factor of various malignances, while MMP8 exhibits an inhibitory effect on tumorigenesis and metastasis. We evaluated the potential association of functional polymorphisms in the promoter of the MMP7 (rs11568818) and MMP8...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 24757528
DOI: 10.5173/ceju.2013.04.art3

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