Article
Effectiveness of preventive interventions in BRCA1/2 gene mutation carriers: a systematic review.
International journal of cancer - 15 Jul 2007
Bermejo-Pérez M J, Márquez-Calderón S, Llanos-Méndez A
Abstract excerpt
A systematic review of the literature was conducted to assess the outcomes of preventive interventions (prophylactic surgery, intensive cancer screening, and chemoprevention) in women who carry mutations in BRCA1/2 genes, in terms of reducing breast and gynaecological cancer incidence and/or mortality. A search for relevant articles published between 1996 and 2005 (inclusive) was run on Medline, Embase and other...
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