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Article

MicroRNA genes are frequently located near mouse cancer susceptibility loci.

Proceedings of the National Academy of Sciences of the United States of America - 8 May 2007

Sevignani Cinzia, Calin George A, Nnadi Stephanie C, Shimizu Masayoshi, Davuluri Ramana V, Hyslop Terry, Demant Peter, Croce Carlo M, Siracusa Linda D

Abstract excerpt

MicroRNAs (miRNAs) are short 19- to 24-nt RNA molecules that have been shown to regulate the expression of other genes in a variety of eukaryotic systems. Abnormal expression of miRNAs has been observed in several human cancers, and furthermore, germ-line and somatic mutations in human miRNAs were recently identified in patients with chronic lymphocytic leukemia. Thus, human miRNAs can act as tumor suppressor...

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Identifiers

PMID: 17470785
DOI: 10.1073/pnas.0702177104
PMCID: PMC1876564

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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