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Article

Use of a synthetic lethal screen to identify genes related to TIF51A in Saccharomyces cerevisiae.

Genetics and molecular research : GMR - 28 Mar 2007

Frigieri M C, Thompson G M, Pandolfi J R, Zanelli C F, Valentini S R

Abstract excerpt

The putative eukaryotic translation initiation factor 5A (eIF5A) is an essential protein for cell viability and the only cellular protein known to contain the unusual amino acid residue hypusine. eIF5A has been implicated in translation initiation, cell proliferation, nucleocytoplasmic transport, mRNA decay, and actin polarization, but the precise biological function of this protein is not clear. However, eIF5A...

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PMID: 17469065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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