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Article

Kir2.6 regulates the surface expression of Kir2.x inward rectifier potassium channels.

The Journal of biological chemistry - 18 Mar 2011

Dassau Lior, Conti Lisa R, Radeke Carolyn M, Ptáček Louis J, Vandenberg Carol A

Abstract excerpt

Precise trafficking, localization, and activity of inward rectifier potassium Kir2 channels are important for shaping the electrical response of skeletal muscle. However, how coordinated trafficking occurs to target sites remains unclear. Kir2 channels are tetrameric assemblies of Kir2.x subunits. By immunocytochemistry we show that endogenous Kir2.1 and Kir2.2 are localized at the plasma membrane and T-tubules...

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Identifiers

PMID: 21209095
DOI: 10.1074/jbc.M110.170597
PMCID: PMC3059001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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