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Article

Patched haploinsufficient mouse rhabdomyosarcoma overexpress secreted phosphoprotein 1 and matrix metalloproteinases.

European journal of cancer (Oxford, England : 1990) - 1 May 2007

De Bortoli Massimiliano, Castellino Robert C, Skapura Darlene G, Shen Jianhe J, Su Jack M, Russell Heidi V, Hicks M John, Man Tsz-Kwong, Kim John Y H

Abstract excerpt

Rhabdomyosarcoma is the most common soft tissue sarcoma of childhood. Improving the management of rhabdomyosarcoma requires a better understanding of growth regulation. Patched haploinsufficient (Ptch+/-) mice spontaneously develop soft tissue sarcomas that resemble human rhabdomyosarcomas. Using microarray profiling and quantitative real-time reverse transcriptase polymerase chain reaction, we identified...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17467979
DOI: 10.1016/j.ejca.2007.02.008

Genes

SPP1

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